Menopausal Hot Flashes: Are SSRIs a Treatment Option?

Many of our patients are seeking nonhormonal remedies for their hot flashes, and it is important to understand whether SSRI or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants are effectively reducing these symptoms. The study I would like to discuss was published earlier this year in JAMA. It was a multicenter, randomized, placebo-controlled trial that was conducted in 205 women.[1] Approximately half of the participants were African American, allowing for a comparison of results by race.

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