"Prevalence and Characteristics of Undiagnosed Bipolar Disorders in Patients With a Major Depressive Episode: The BRIDGE Study
Angst J, Azorin JM, Bowden CL, et al
Arch Gen Psychiatry. 2011;68:791-798
Study Summary
Many patients with major depressive episodes (MDEs) who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do not include mood stabilizers. The objective of this multicenter, multinational, transcultural, cross-sectional, diagnostic study was to quantify how often bipolar disorder symptoms are encountered in patients seeking treatment for an MDE. Included were 5635 adults seen for an MDE at community and hospital psychiatry departments. A total of 903 patients fulfilled DSM-IV-TR criteria for bipolar disorder (16.0%; 95% confidence interval, 15.1%-17.0%), whereas 2647 (47.0%; 95% confidence interval, 45.7%-48.3%) met an alternate set of criteria for bipolarity called the "bipolarity specifier" criteria."
Angst J, Azorin JM, Bowden CL, et al
Arch Gen Psychiatry. 2011;68:791-798
Study Summary
Many patients with major depressive episodes (MDEs) who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do not include mood stabilizers. The objective of this multicenter, multinational, transcultural, cross-sectional, diagnostic study was to quantify how often bipolar disorder symptoms are encountered in patients seeking treatment for an MDE. Included were 5635 adults seen for an MDE at community and hospital psychiatry departments. A total of 903 patients fulfilled DSM-IV-TR criteria for bipolar disorder (16.0%; 95% confidence interval, 15.1%-17.0%), whereas 2647 (47.0%; 95% confidence interval, 45.7%-48.3%) met an alternate set of criteria for bipolarity called the "bipolarity specifier" criteria."
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